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Reducing dehydroascorbic acid back to ascorbic acid is the opposite reaction

[DOI] [PMC free article] [PubMed] [Google Scholar] 247.Zoeller R.T., Brown T.R., Doan L.L., Gore A.C., Skakkebaek N.E., Soto A.M., Woodruff T.J., Vom Saal F.S

Further studies found that AUF1 interacts with the coding sequence and 3-untranslated region (UTR) of Nrf2 to stabilise the gene, whereas AUF1 binding to the 3-UTR of activating transcription factor 3 ( ATF3 ) promotes degradation of the gene, producing an anti-ferroptosis effect and ameliorating ALI [68]